RDS Cover Image

Cover Image Vol 6 No 2: Section from the pancreatic tail region of a 12 year old male patient with 1 year of clinical diabetes, who died of ketoacidosis. The strong hyperexpression of MHC Class I (HLA-ABC) on all islet cells is obvious, while many β-cells continue to produce insulin. This islet was found to contain limited numbers of infiltrating CD8 T cells.