Rev Diabet Stud, 2009, 6(2):76-80 DOI 10.1900/RDS.2009.6.76

Breakthrough in Diabetes Therapy ... Just Around the Corner?

William A. Rudert, Massimo Trucco

Division of Immunogenetics, Department of Pediatrics, ChildrenĀ“s Hospital of Pittsburgh Rangos Research Center, Pittsburgh, PA 15224, USA
Address correspondence to: Massimo Trucco, e-mail: mnt@pitt.edu

Manuscript submitted August 1, 2009; resubmitted September 7, 2009; accepted September 9, 2009.

Keywords: type 1 diabetes, beta-cell regeneration, T lymphocyte, antibody, autoimmunity, aCD3, aCD4, regulatory T cell, B cell, rituximab, transplantation


Inspired by the articles presented in this issue of The Review of Diabetic Studies, we considered it useful to summarize the latest achievements and current challenges we face in the search for a cure of type 1 diabetes. In this editorial article, we took into account how the research landscape has changed in only a few years. While modern lifestyles impose new concerns, now we have a better knowledge of the various aspects of the disease that can be used to treat our young patients with more appropriate approaches, thereby eliminating old and obsolete prejudices.

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