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Rev Diabet Stud, 2017, 14(2-3):269-278 DOI 10.1900/RDS.2017.14.269

The Role of Iron in Type 1 Diabetes Etiology: A Systematic Review of New Evidence on a Long-Standing Mystery

Karen L. Søgaard1, Christina Ellervik2,3,4,5, Jannet Svensson1,3, Steffen U. Thorsen1

1Copenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730 Herlev, Denmark
2Department of Production, Research, and Innovation; Region Zealand, Alleen 15, 4180 Sorø, Denmark
3Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark
4Department of Laboratory Medicine, Boston Children`s Hospital, 300 Longwood Avenue, 02115, Boston, MA, USA
5Harvard Medical School, 25 Shattuck St, 02115, Boston, MA, USA
Address correspondence to: Karen L. Søgaard, e-mail:

Manuscript submitted April 18, 2017; resubmitted July 13, 2017; accepted August 24, 2017.

Keywords: type 1 diabetes, iron overload, iron intake, risk factor, insulin, systematic review

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