Review

Rev Diabet Stud, 2017, 14(1):39-50 DOI 10.1900/RDS.2017.14.39

The Nexus of Stem Cell-Derived Beta-Cells and Genome Engineering

Sara D. Sackett, Aida Rodriguez, Jon S. Odorico

Division of Transplantation, Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Ave, Madison, WI 53711, USA
Address correspondence to: Sara Dutton Sackett, email: sackett@surgery.wisc.edu

Manuscript submitted June 11, 2017; accepted June 11, 2017.

Keywords: diabetes, beta-cell, islet, CRISPR, pluripotent stem cell, GWAS, autoimmunity, allograft rejection, HLA molecules, custom-engineered nuclease

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