Review

Rev Diabet Stud, 2017, 14(1):22-38 DOI 10.1900/RDS.2017.14.22

Enzyme Development for Human Islet Isolation: Five Decades of Progress or Stagnation?

Daniel Brandhorst, Heide Brandhorst, Paul R.V. Johnson

Nuffield Department of Surgical Sciences, University of Oxford, United Kingdom
Address correspondence to: Daniel Brandhorst, Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Level 6, Headley Way, OX3 9DU, Oxford, United Kingdom, email: Daniel.Brandhorst@nds.ox.ac.uk

Manuscript submitted June 7, 2017; accepted June 9, 2017.

Keywords: diabetes, collagenase, islet isolation, neutral protease, thermolysin, tryptic-like activity, clostripain, extracellular matrix protein, basement membrane

Abstract (FREE). Full-text access requires a subscription to The Review of Diabetic Studies.

To view full-text, select one of the options below:

Login if you are subscriber:

 

Purchase short-term access:

Username

 

  • Pay per Article for 1 day for EUR 25.00.
  • Pay for Admission to all content in The Review of Diabetic Studies for 5 days for EUR 40.00.
  • Regain Access - You can regain access to a recent Pay per Article or Pay for Admission purchase if your access period has not yet expired.
Password
   Having trouble logging in? Be sure to enable cookies in your web browser.
 
Forgot your user name or password?

 

 

Sign in for subscription:

 

   Subscribe to the journal.